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Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers

The mature envelope glycoprotein (Env) spike on the surfaces of human immunodeficiency virus type 1 (HIV-1)-infected cells and virions is derived from proteolytic cleavage of a trimeric gp160 glycoprotein precursor. In these studies, we compared the conformations of cleaved and uncleaved membrane En...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Castillo-Menendez, Luis R., Witt, Kristen, Espy, Nicole, Princiotto, Amy, Madani, Navid, Pacheco, Beatriz, Finzi, Andrés, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5974486/
https://ncbi.nlm.nih.gov/pubmed/29618643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00277-18
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