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Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer
The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) trimer, a membrane-fusing machine, mediates virus entry into host cells and is the sole virus-specific target for neutralizing antibodies. Binding the receptors, CD4 and CCR5/CXCR4, triggers Env conformational changes from t...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725050/ https://ncbi.nlm.nih.gov/pubmed/23757493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307382110 |
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