Chargement en cours...
A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry
Binding to the primary receptor, CD4, triggers conformational changes in the metastable envelope glycoprotein (Env) trimer (gp120(3)/gp41(3)) of human immunodeficiency virus (HIV-1) that are important for virus entry into host cells. These changes include an “opening” of the trimer, creation of a bi...
Enregistré dans:
| Publié dans: | Nat Chem Biol |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231716/ https://ncbi.nlm.nih.gov/pubmed/25174000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1623 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|