Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

Human immunodeficiency virus type 1 (HIV-1) has evolved a sophisticated strategy to conceal conserved epitopes of its envelope glycoproteins (Env) recognized by antibody-dependent cellular cytotoxicity (ADCC)-mediating antibodies. These antibodies, which are present in the sera of most HIV-1-infecte...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Richard, Jonathan, Pacheco, Beatriz, Gohain, Neelakshi, Veillette, Maxime, Ding, Shilei, Alsahafi, Nirmin, Tolbert, William D., Prévost, Jérémie, Chapleau, Jean-Philippe, Coutu, Mathieu, Jia, Manxue, Brassard, Nathalie, Park, Jongwoo, Courter, Joel R., Melillo, Bruno, Martin, Loïc, Tremblay, Cécile, Hahn, Beatrice H., Kaufmann, Daniel E., Wu, Xueling, Smith, Amos B., Sodroski, Joseph, Pazgier, Marzena, Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078604/
https://ncbi.nlm.nih.gov/pubmed/27633463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.09.004
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