Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

The HIV-1 envelope glycoprotein (Env) trimer mediates cell entry and is conformationally dynamic(1–8). Imaging by single-molecule fluorescence resonance energy transfer (smFRET) has revealed that, on the surface of intact virions, mature pre-fusion Env transitions from a pre-triggered conformation (...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nature
Autori principali: Lu, Maolin, Ma, Xiaochu, Castillo-Menendez, Luis R., Gorman, Jason, Alsahafi, Nirmin, Ermel, Utz, Terry, Daniel S., Chambers, Michael, Peng, Dongjun, Zhang, Baoshan, Zhou, Tongqing, Reichard, Nick, Wang, Kevin, Grover, Jonathan R., Carman, Brennan P., Gardner, Matthew R., Nikic-Spiegel, Ivana, Sugawara, Akihiro, Arthos, James, Lemke, Edward A., Smith, Amos B., Farzan, Michael, Abrams, Cameron, Munro, James B., McDermott, Adrian B., Finzi, Andrés, Kwong, Peter D., Blanchard, Scott C., Sodroski, Joseph G., Mothes, Walther
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6655592/
https://ncbi.nlm.nih.gov/pubmed/30971821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1101-y
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi