Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity

Impairment of Nef function, including reduced CD4 downregulation, was described in a subset of HIV-1-infected individuals that control viral replication without antiretroviral treatment (elite controllers [EC]). Elimination of HIV-1-infected cells by antibody-dependent cellular cytotoxicity (ADCC) r...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Alsahafi, Nirmin, Ding, Shilei, Richard, Jonathan, Markle, Tristan, Brassard, Nathalie, Walker, Bruce, Lewis, George K., Kaufmann, Daniel E., Brockman, Mark A., Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810628/
https://ncbi.nlm.nih.gov/pubmed/26719277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02973-15
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