Attenuation of multiple Nef functions in HIV-1 elite controllers

BACKGROUND: Impaired HIV-1 Gag, Pol, and Env function has been described in elite controllers (EC) who spontaneously suppress plasma viremia to < 50 RNA copies/mL; however, activity of the accessory protein Nef remains incompletely characterized. We examined the ability of 91 Nef clones, isolated...

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Hauptverfasser: Mwimanzi, Philip, Markle, Tristan J, Martin, Eric, Ogata, Yoko, Kuang, Xiaomei T, Tokunaga, Michiyo, Mahiti, Macdonald, Pereyra, Florencia, Miura, Toshiyuki, Walker, Bruce D, Brumme, Zabrina L, Brockman, Mark A, Ueno, Takamasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564836/
https://ncbi.nlm.nih.gov/pubmed/23289738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-1
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