Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

HIV-1 Nef binds to the cytoplasmic region of HLA-A and HLA-B and downregulates these molecules from the surface of virus-infected cells, thus evading immune detection by CD8(+) T cells. Polymorphic residues within the HLA cytoplasmic region may affect Nef’s downregulation activity. However, the effe...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Mahiti, Macdonald, Toyoda, Mako, Jia, Xiaofei, Kuang, Xiaomei T., Mwimanzi, Francis, Mwimanzi, Philip, Walker, Bruce D., Xiong, Yong, Brumme, Zabrina L., Brockman, Mark A., Ueno, Takamasa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Microbiology 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724998/
https://ncbi.nlm.nih.gov/pubmed/26787826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01516-15
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller