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Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation
The HIV-1 envelope glycoprotein (Env) trimer [(gp120/gp41)(3)] is a metastable complex expressed at the surface of viral particles and infected cells that samples different conformations. Before engaging CD4, Env adopts an antibody-resistant “closed” conformation (State 1). CD4 binding triggers an i...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092833/ https://ncbi.nlm.nih.gov/pubmed/33298541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01620-20 |
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