Epidermal growth factor receptor targeting and challenges in glioblastoma

Por Thorne, Amy Haseley, Zanca, Ciro, Furnari, Frank
Publicado no Neuro Oncol (2016)

Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks

Por Gomez, German G., Wykosky, Jill, Zanca, Ciro, Furnari, Frank B., Cavenee, Webster K.
Publicado em 2013

Vitamin D(3) signalling in the brain enhances the function of phosphoprotein enriched in astrocytes – 15 kD (PEA-15)

Por Obradovic, Darja, Zanca, Ciro, Vogl, Annette, Trümbach, Dietrich, Deussing, Jan, Condorelli, Gerolama, Rein, Theo
Publicado no J Cell Mol Med (2009)

A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments

Por Masui, Kenta, Gini, Beatrice, Wykosky, Jill, Zanca, Ciro, Mischel, Paul S., Furnari, Frank B., Cavenee, Webster K.
Publicado em 2013

CBIO-04 DAXX INHIBITION SUPPRESSES TUMOR GROWTH IN PTEN-DEFICIENT HUMAN GLIOBLASTOMAS

Por Benitez, Jorge, Boyer, Antonia, Camargo, Fernanda, Zanca, Ciro, Ma, Jianhui, Jameson, Nathan, Cavenee, Webster, Furnari, Frank
Publicado no Neuro Oncol (2015)

MUTANT EGFR SUPPRESSION OF MICRORNA-9 INDUCES FOXP1 TO ENHANCE GLIOBLASTOMA TUMORIGENICITY

Por Furnari, Frank, Gomez, German, Volinia, Stefano, Croce, Carlo, Zanca, Ciro, Li, Ming, Gutmann, David, Brennan, Cameron, Cavenee, Webster
Publicado em 2014

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation

Por Romano, Giulia, Acunzo, Mario, Garofalo, Michela, Di Leva, Gianpiero, Cascione, Luciano, Zanca, Ciro, Bolon, Brad, Condorelli, Gerolama, Croce, Carlo M.
Publicado em 2012

Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Por Garofalo, Michela, Quintavalle, Cristina, Zanca, Ciro, De Rienzo, Assunta, Romano, Giulia, Acunzo, Mario, Puca, Loredana, Incoronato, Mariarosaria, Croce, Carlo M., Condorelli, Gerolama
Publicado em 2008

Suppression of MicroRNA-9 by Mutant EGFR Signaling Upregulates FOXP1 to Enhance Glioblastoma Tumorigenicity

Por Gomez, German G., Volinia, Stefano, Croce, Carlo M., Zanca, Ciro, Li, Ming, Emnett, Ryan, Gutmann, David H., Brennan, Cameron W., Furnari, Frank B., Cavenee, Webster K
Publicado em 2014

Hsc70 binds and directs the non-phosphorylated tumor-suppressor form of PED to Chaperone-Mediated Autophagy (CMA) degradation in lung cancer

Por Quintavalle, Cristina, Costanzo, Stefania Di, Zanca, Ciro, Tasset, Immaculada, Fraldi, Alessandro, Incoronato, Mariarosaria, Mirabelli, Peppino, Monti, Maria, Ballabio, Andrea, Pucci, Piero, Cuervo, Ana Maria, Condorelli, Gerolama
Publicado no J Cell Physiol (2014)

PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancer

Por Zanca, Ciro, Garofalo, Michela, Quintavalle, Cristina, Romano, Giulia, Acunzo, Mario, Ragno, Pia, Montuori, Nunzia, Incoronato, Mariarosaria, Tornillo, Luigi, Baumhoer, Daniel, Briguori, Carlo, Terracciano, Luigi, Condorelli, Gerolama
Publicado no J Cell Mol Med (2008)

Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

Por Antal, Corina E., Hudson, Andrew M., Kang, Emily, Zanca, Ciro, Wirth, Christopher, Stephenson, Natalie L., Trotter, Eleanor W., Gallegos, Lisa L., Miller, Crispin J., Furnari, Frank B., Hunter, Tony, Brognard, John, Newton, Alexandra C.
Publicado no Cell (2015)

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies

Por Iwanami, Akio, Gini, Beatrice, Zanca, Ciro, Matsutani, Tomoo, Assuncao, Alvaro, Nael, Ali, Dang, Julie, Yang, Huijun, Zhu, Shaojun, Kohyama, Jun, Kitabayashi, Issay, Cavenee, Webster K., Cloughesy, Timothy F., Furnari, Frank B., Nakamura, Masaya, Toyama, Yoshiaki, Okano, Hideyuki, Mischel, Paul S.
Publicado em 2013

EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling

Por Liu, Feng, Hon, Gary C., Villa, Genaro R., Turner, Kristen M., Ikegami, Shiro, Yang, Huijun, Ye, Zhen, Li, Bin, Kuan, Samantha, Lee, Ah Young, Zanca, Ciro, Wei, Bowen, Lucey, Greg, Jenkins, David, Zhang, Wei, Barr, Cathy L., Furnari, Frank B., Cloughesy, Timothy F., Yong, William H., Gahman, Timothy C., Shiau, Andrew K., Cavenee, Webster K., Ren, Bing, Mischel, Paul S.
Publicado no Mol Cell (2015)

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas

Por Gini, Beatrice, Zanca, Ciro, Guo, Deliang, Matsutani, Tomoo, Masui, Kenta, Ikegami, Shiro, Yang, Huijun, Nathanson, David, Villa, Genaro R., Shackelford, David, Zhu, Shaojun, Tanaka, Kazuhiro, Babic, Ivan, Akhavan, David, Lin, Kelly, Assuncao, Alvaro, Gu, Yuchao, Bonetti, Bruno, Mortensen, Deborah S., Xu, Shuichan, Raymon, Heather K., Cavenee, Webster K., Furnari, Frank B, James, David, Kroemer, Guido, Heath, James, Hege, Kristen, Chopra, Rajesh, Cloughesy, Timothy, Mischel, Paul S.
Publicado em 2013