Recombinant inbred systems can advance research in behavioral ecology

著者: Gini, Beatrice, Hager, Reinmar
出版事項 2012

Greater than the sum of its parts: Single nucleus sequencing identifies convergent evolution of independent EGFR mutants in GBM

著者: Gini, Beatrice, Mischel, Paul S.
出版年 Cancer Discov (2014)

Genetic variation in offspring indirectly influences the quality of maternal behaviour in mice

著者: Ashbrook, David George, Gini, Beatrice, Hager, Reinmar
出版年 eLife (2015)

Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer

著者: Gini, Beatrice, Thomas, Nicholas, Blakely, Collin M.
出版年 J Thorac Dis (2020)

A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments

著者: Masui, Kenta, Gini, Beatrice, Wykosky, Jill, Zanca, Ciro, Mischel, Paul S., Furnari, Frank B., Cavenee, Webster K.
出版事項 2013

NT-39 GLUTAMINASE-MEDIATED METABOLIC PATHWAY INVOLVES GLIOBLASTOMA RESISTANCE TO mTOR-TARGETED THERAPIES

著者: Tanaka, Kazuhiro, Sasayama, Takashi, Irino, Yasuhiro, Takata, Kumi, Nagashima, Hiroaki, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Mischel, Paul S., Kohmura, Eiji
出版事項 2014

Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1Tesla

著者: Chaumeil, Myriam M., Gini, Beatrice, Yang, Huijun, Iwanami, Akio, Sukumar, Subramaniam, Ozawa, Tomoko, Pieper, Russel O., Mischel, Paul S., James, C. David, Berger, Mitchel S., Ronen, Sabrina M.
出版事項 2012

Saccharomyces jurei sp. nov., isolation and genetic identification of a novel yeast species from Quercus robur

著者: Naseeb, Samina, James, Stephen A., Alsammar, Haya, Michaels, Christopher J., Gini, Beatrice, Nueno-Palop, Carmen, Bond, Christopher J., McGhie, Henry, Roberts, Ian N., Delneri, Daniela
出版年 Int J Syst Evol Microbiol (2017)

Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment

著者: Tanaka, Kazuhiro, Sasayama, Takashi, Irino, Yasuhiro, Takata, Kumi, Nagashima, Hiroaki, Satoh, Naoko, Kyotani, Katsusuke, Mizowaki, Takashi, Imahori, Taichiro, Ejima, Yasuo, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Hosoda, Kohkichi, Sasaki, Ryohei, Mischel, Paul S., Kohmura, Eiji
出版年 J Clin Invest (2015)

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies

著者: Iwanami, Akio, Gini, Beatrice, Zanca, Ciro, Matsutani, Tomoo, Assuncao, Alvaro, Nael, Ali, Dang, Julie, Yang, Huijun, Zhu, Shaojun, Kohyama, Jun, Kitabayashi, Issay, Cavenee, Webster K., Cloughesy, Timothy F., Furnari, Frank B., Nakamura, Masaya, Toyama, Yoshiaki, Okano, Hideyuki, Mischel, Paul S.
出版事項 2013

mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT

著者: Gu, Yuchao, Albuquerque, Claudio P., Braas, Daniel, Zhang, Wei, Villa, Genaro R., Bi, Junfeng, Ikegami, Shiro, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Gahman, Timothy C., Shiau, Andrew K., Cloughesy, Timothy F., Christofk, Heather R., Zhou, Huilin, Guan, Kun-Liang, Mischel, Paul S.
出版年 Mol Cell (2017)

mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

著者: Masui, Kenta, Tanaka, Kazuhiro, Akhavan, David, Babic, Ivan, Gini, Beatrice, Matsutani, Tomoo, Iwanami, Akio, Liu, Feng, Villa, Genaro R., Gu, Yuchao, Campos, Carl, Zhu, Shaojun, Yang, Huijun, Yong, William H., Cloughesy, Timothy F., Mellinghoff, Ingo K., Cavenee, Webster K., Shaw, Reuben J., Mischel, Paul S.
出版事項 2013

Inactivation of Capicua drives cancer metastasis

著者: Okimoto, Ross A., Breitenbuecher, Frank, Olivas, Victor R., Wu, Wei, Gini, Beatrice, Hofree, Matan, Asthana, Saurabh, Hrustanovic, Gorjan, Flanagan, Jennifer, Tulpule, Asmin, Blakely, Collin M., Haringsma, Henry J., Simmons, Andrew D., Gowen, Kyle, Suh, James, Miller, Vincent A., Ali, Siraj, Schuler, Martin, Bivona, Trever G.
出版年 Nat Genet (2016)

Single cell phosphoproteomics resolves adaptive signaling dynamics and informs targeted combination therapy in glioblastoma

著者: Wei, Wei, Shin, Young Shik, Xue, Min, Matsutani, Tomoo, Masui, Kenta, Yang, Huijun, Ikegami, Shiro, Gu, Yuchao, Ken, Herrmann, Johnson, Dazy, Ding, Xiangming, Hwang, Kiwook, Kim, Jungwoo, Zhou, Jian, Su, Yapeng, Li, Xinmin, Bonetti, Bruno, Chopra, Rajesh, James, C. David, Cavenee, Webster K., Cloughesy, Timothy F., Mischel, Paul S., Heath, James R., Gini, Beatrice
出版年 Cancer Cell (2016)

Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance

著者: Tanaka, Kazuhiro, Babic, Ivan, Nathanson, David, Akhavan, David, Guo, Deliang, Gini, Beatrice, Dang, Julie, Zhu, Shaojun, Yang, Huijun, de Jesus, Jason, Amzajerdi, Ali Nael, Zhang, Yinan, Dibble, Christian C., Dan, Hancai, Rinkenbaugh, Amanda, Yong, William H., Vinters, Harry V., Gera, Joseph F., Cavenee, Webster K., Cloughesy, Timothy F., Manning, Brendan D., Baldwin, Albert S., Mischel, Paul S.
出版事項 2011

EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer

著者: Babic, Ivan, Anderson, Erik S., Tanaka, Kazuhiro, Guo, Deliang, Masui, Kenta, Li, Bing, Zhu, Shaojun, Gu, Yuchao, Villa, Genaro, Akhavan, David, Nathanson, David, Gini, Beatrice, Mareninov, Sergey, Li, Rui, Espindola C., Carolina, Kurdistani, Siavash K., Eskin, Ascia, Nelson, Stanley F., Yong, William H., Cavenee, Webster K., Cloughesy, Timothy F., Christofk, Heather R., Black, Douglas L., Mischel, Paul S.
出版事項 2013

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

著者: Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Eskin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
出版事項 2013

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas

著者: Gini, Beatrice, Zanca, Ciro, Guo, Deliang, Matsutani, Tomoo, Masui, Kenta, Ikegami, Shiro, Yang, Huijun, Nathanson, David, Villa, Genaro R., Shackelford, David, Zhu, Shaojun, Tanaka, Kazuhiro, Babic, Ivan, Akhavan, David, Lin, Kelly, Assuncao, Alvaro, Gu, Yuchao, Bonetti, Bruno, Mortensen, Deborah S., Xu, Shuichan, Raymon, Heather K., Cavenee, Webster K., Furnari, Frank B, James, David, Kroemer, Guido, Heath, James, Hege, Kristen, Chopra, Rajesh, Cloughesy, Timothy, Mischel, Paul S.
出版事項 2013

An LXR agonist promotes GBM cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway

著者: Guo, Deliang, Reinitz, Felicia, Youssef, Mary, Hong, Cynthia, Nathanson, David, Akhavan, David, Kuga, Daisuke, Amzajerdi, Ali Nael, Soto, Horacio, Zhu, Shaojun, Babic, Ivan, Tanaka, Kazuhiro, Dang, Julie, Iwanami, Akio, Gini, Beatrice, DeJesus, Jason, Lisiero, Dominique D., Huang, Tiffany T., Prins, Robert M., Wen, Patrick Y., Robins, H. Ian, Prados, Michael D., DeAngelis, Lisa M., Mellinghoff, Ingo K., Mehta, Minesh P., James, C. David, Chakravarti, Arnab, Cloughesy, Timothy F., Tontonoz, Peter, Mischel, Paul S.
出版事項 2011

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

著者: Blakely, Collin M., Watkins, Thomas B.K., Wu, Wei, Gini, Beatrice, Chabon, Jacob J., McCoach, Caroline E., McGranahan, Nicholas, Wilson, Gareth A., Birkbak, Nicolai J., Olivas, Victor R., Rotow, Julia, Maynard, Ashley, Wang, Victoria, Gubens, Matthew A., Banks, Kimberly C., Lanman, Richard B., Caulin, Aleah F., John, John St., Cordero, Anibal R., Giannikopoulos, Petros, Simmons, Andrew D., Mack, Philip C., Gandara, David R., Husain, Hatim, Doebele, Robert C., Riess, Jonathan W., Diehn, Maximilian, Swanton, Charles, Bivona, Trever G.
出版年 Nat Genet (2017)