The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting

Por Wykosky, Jill, Debinski, Waldemar
Publicado em 2008

Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations

Por Wykosky, Jill, Fenton, Tim, Furnari, Frank, Cavenee, Webster K.
Publicado em 2011

EphrinA1 Is Released in Three Forms from Cancer Cells by Matrix Metalloproteases

Por Beauchamp, Amanda, Lively, Mark O., Mintz, Akiva, Gibo, Denise, Wykosky, Jill, Debinski, Waldemar
Publicado em 2012

Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks

Por Gomez, German G., Wykosky, Jill, Zanca, Ciro, Furnari, Frank B., Cavenee, Webster K.
Publicado em 2013

Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence

Por Mukasa, Akitake, Wykosky, Jill, Ligon, Keith L., Chin, Lynda, Cavenee, Webster K., Furnari, Frank
Publicado em 2010

A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments

Por Masui, Kenta, Gini, Beatrice, Wykosky, Jill, Zanca, Ciro, Mischel, Paul S., Furnari, Frank B., Cavenee, Webster K.
Publicado em 2013

Structural and Functional Characterization of Monomeric EphrinA1 Binding Site to EphA2 Receptor

Por Lema Tomé, Carla M., Palma, Enzo, Ferluga, Sara, Lowther, W. Todd, Hantgan, Roy, Wykosky, Jill, Debinski, Waldemar
Publicado em 2012

A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

Por Read, Renee D., Fenton, Tim R., Gomez, German G., Wykosky, Jill, Vandenberg, Scott R., Babic, Ivan, Iwanami, Akio, Yang, Huijun, Cavenee, Webster K., Mischel, Paul S., Furnari, Frank B., Thomas, John B.
Publicado em 2013

A Urokinase Receptor-Bim Signaling Axis Emerges During EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma

Por Wykosky, Jill, Hu, Jingjing, Gomez, German G., Taylor, Tiffany, Villa, Genaro R., Pizzo, Donald, VandenBerg, Scott R., Thorne, Amy Haseley, Chen, Clark C., Mischel, Paul S., Gonias, Steven. L., Cavenee, Webster K., Furnari, Frank B.
Publicado no Cancer Res (2014)

Emerging insights into the molecular and cellular basis of glioblastoma

Por Dunn, Gavin P., Rinne, Mikael L., Wykosky, Jill, Genovese, Giannicola, Quayle, Steven N., Dunn, Ian F., Agarwalla, Pankaj K., Chheda, Milan G., Campos, Benito, Wang, Alan, Brennan, Cameron, Ligon, Keith L., Furnari, Frank, Cavenee, Webster K., Depinho, Ronald A., Chin, Lynda, Hahn, William C.
Publicado em 2012

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition

Por Shen, Ying, Li, Jie, Nitta, Masayuki, Futalan, Diahnn, Steed, Tyler, Treiber, Jeffrey M., Taich, Zack, Stevens, Deanna, Wykosky, Jill, Chen, Hong-Zhuan, Carter, Bob S., Becher, Oren J., Kennedy, Richard, Esashi, Fumiko, Sarkaria, Jann N., Furnari, Frank B., Cavenee, Webster K., Desai, Arshad, Chen, Clark C.
Publicado no Oncotarget (2015)

Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240

Por Fenton, Tim R., Nathanson, David, Ponte de Albuquerque, Claudio, Kuga, Daisuke, Iwanami, Akio, Dang, Julie, Yang, Huijun, Tanaka, Kazuhiro, Oba-Shinjo, Sueli Mieko, Uno, Miyuki, del Mar Inda, Maria, Wykosky, Jill, Bachoo, Robert M., James, C. David, DePinho, Ronald A., Vandenberg, Scott R., Zhou, Huilin, Marie, Suely K. N., Mischel, Paul S., Cavenee, Webster K., Furnari, Frank B.
Publicado em 2012

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

Por Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Eskin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
Publicado em 2013