EphrinA1 Is Released in Three Forms from Cancer Cells by Matrix Metalloproteases

EphrinA1 is a glycosylphosphatidylinositol (GPI)-linked ligand for the EphA2 receptor, which is overexpressed in glioblastoma (GBM), among other cancers. Activation of the receptor by ephrinA1 leads to a suppression of oncogenic properties of GBM cells. We documented that a monomeric functional form...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beauchamp, Amanda, Lively, Mark O., Mintz, Akiva, Gibo, Denise, Wykosky, Jill, Debinski, Waldemar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434542/
https://ncbi.nlm.nih.gov/pubmed/22688511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06791-11
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg