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Structural and Functional Characterization of Monomeric EphrinA1 Binding Site to EphA2 Receptor
The EphA2 receptor is overexpressed in glioblastoma multiforme and has been to shown to contribute to cell transformation, tumor initiation, progression, and maintenance. EphrinA1 (eA1) is a preferred ligand for the receptor. Treatment with monomeric eA1, the form of eA1 found in the extracellular e...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340174/ https://ncbi.nlm.nih.gov/pubmed/22362770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311670 |
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