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Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks

Receptor tyrosine kinases (RTKs) such as the epidermal growth factor receptor (EGFR) regulate cellular homeostatic processes. EGFR activates downstream signaling cascades that promote tumor cell survival, proliferation and migration. Dysregulation of EGFR signaling as a consequence of overexpression...

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Bibliografische gegevens
Hoofdauteurs: Gomez, German G., Wykosky, Jill, Zanca, Ciro, Furnari, Frank B., Cavenee, Webster K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Chinese Anti-Cancer Association 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860350/
https://ncbi.nlm.nih.gov/pubmed/24349829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7497/j.issn.2095-3941.2013.04.003
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