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Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations
Epidermal growth factor receptor (EGFR) is one of the most commonly altered genes in human cancer by way of over-expression, amplification, and mutation. Targeted inhibition of EGFR activity suppresses signal transduction pathways which control tumor cell growth, proliferation, and resistance to apo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Sun Yat-sen University Cancer Center
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359794/ https://ncbi.nlm.nih.gov/pubmed/21192840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.010.10542 |
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