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Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

As tumours evolve, the daughter cells of the initiating cell often become molecularly heterogeneous and develop different functional properties and therapeutic vulnerabilities. In glioblastoma (GBM), a lethal form of brain cancer, the heterogeneous expression of the epidermal growth factor receptor...

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Dades bibliogràfiques
Publicat a:Nat Rev Cancer
Autors principals: Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875778/
https://ncbi.nlm.nih.gov/pubmed/25855404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3918
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