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Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

As tumours evolve, the daughter cells of the initiating cell often become molecularly heterogeneous and develop different functional properties and therapeutic vulnerabilities. In glioblastoma (GBM), a lethal form of brain cancer, the heterogeneous expression of the epidermal growth factor receptor...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875778/
https://ncbi.nlm.nih.gov/pubmed/25855404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3918
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