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Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

As tumours evolve, the daughter cells of the initiating cell often become molecularly heterogeneous and develop different functional properties and therapeutic vulnerabilities. In glioblastoma (GBM), a lethal form of brain cancer, the heterogeneous expression of the epidermal growth factor receptor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Cancer
Prif Awduron: Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875778/
https://ncbi.nlm.nih.gov/pubmed/25855404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3918
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