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Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

As tumours evolve, the daughter cells of the initiating cell often become molecularly heterogeneous and develop different functional properties and therapeutic vulnerabilities. In glioblastoma (GBM), a lethal form of brain cancer, the heterogeneous expression of the epidermal growth factor receptor...

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Podrobná bibliografie
Vydáno v:Nat Rev Cancer
Hlavní autoři: Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875778/
https://ncbi.nlm.nih.gov/pubmed/25855404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3918
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