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Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma

As tumours evolve, the daughter cells of the initiating cell often become molecularly heterogeneous and develop different functional properties and therapeutic vulnerabilities. In glioblastoma (GBM), a lethal form of brain cancer, the heterogeneous expression of the epidermal growth factor receptor...

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Bibliografiske detaljer
Udgivet i:Nat Rev Cancer
Main Authors: Furnari, Frank B., Cloughesy, Timothy F., Cavenee, Webster K., Mischel, Paul S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875778/
https://ncbi.nlm.nih.gov/pubmed/25855404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3918
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