Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

von Carthy, Jon M., Stöter, Martin, Bellomo, Claudia, Vanlandewijck, Michael, Heldin, Angelos, Morén, Anita, Kardassis, Dimitris, Gahman, Timothy C., Shiau, Andrew K., Bickle, Marc, Zerial, Marino, Heldin, Carl-Henrik, Moustakas, Aristidis
Veröffentlicht in Sci Rep (2016)

Inhibition of Inducible Nitric Oxide Synthase Expression by a Novel Small Molecule Activator of the Unfolded Protein Response

von Symons, Kent T, Massari, Mark E, Dozier, Sara J, Nguyen, Phan M, Jenkins, David, Herbert, Mark, Gahman, Timothy C, Noble, Stewart A, Rozenkrants, Natasha, Zhang, Yan, Rao, Tadimeti S, Shiau, Andrew K, Hassig, Christian A
Veröffentlicht 2008

A Cell Biologist’s Field Guide to Aurora Kinase Inhibitors

von de Groot, Christian O., Hsia, Judy E., Anzola, John V., Motamedi, Amir, Yoon, Michelle, Wong, Yao Liang, Jenkins, David, Lee, Hyun J., Martinez, Mallory B., Davis, Robert L., Gahman, Timothy C., Desai, Arshad, Shiau, Andrew K.
Veröffentlicht in Front Oncol (2015)

Reversible centriole depletion with an inhibitor of Polo-like kinase 4

von Wong, Yao Liang, Anzola, John V., Davis, Robert L., Yoon, Michelle, Motamedi, Amir, Kroll, Ashley, Seo, Chanmee P., Hsia, Judy E., Kim, Sun K., Mitchell, Jennifer W., Mitchell, Brian J., Desai, Arshad, Gahman, Timothy C., Shiau, Andrew K., Oegema, Karen
Veröffentlicht in Science (2015)

mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT

von Gu, Yuchao, Albuquerque, Claudio P., Braas, Daniel, Zhang, Wei, Villa, Genaro R., Bi, Junfeng, Ikegami, Shiro, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Gahman, Timothy C., Shiau, Andrew K., Cloughesy, Timothy F., Christofk, Heather R., Zhou, Huilin, Guan, Kun-Liang, Mischel, Paul S.
Veröffentlicht in Mol Cell (2017)

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

von Boselli, Monica, Lee, Byung-Hoon, Robert, Jessica, Prado, Miguel A., Min, Sang-Won, Cheng, Chialin, Silva, M. Catarina, Seong, Changhyun, Elsasser, Suzanne, Hatle, Ketki M., Gahman, Timothy C., Gygi, Steven P., Haggarty, Stephen J., Gan, Li, King, Randall W., Finley, Daniel
Veröffentlicht in J Biol Chem (2017)

EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling

von Liu, Feng, Hon, Gary C., Villa, Genaro R., Turner, Kristen M., Ikegami, Shiro, Yang, Huijun, Ye, Zhen, Li, Bin, Kuan, Samantha, Lee, Ah Young, Zanca, Ciro, Wei, Bowen, Lucey, Greg, Jenkins, David, Zhang, Wei, Barr, Cathy L., Furnari, Frank B., Cloughesy, Timothy F., Yong, William H., Gahman, Timothy C., Shiau, Andrew K., Cavenee, Webster K., Ren, Bing, Mischel, Paul S.
Veröffentlicht in Mol Cell (2015)

Inhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair

von Ma, Jianhui, Benitez, Jorge A., Li, Jie, Miki, Shunichiro, Ponte de Albuquerque, Claudio, Galatro, Thais, Orellana, Laura, Zanca, Ciro, Reed, Rachel, Boyer, Antonia, Koga, Tomoyuki, Varki, Nissi M., Fenton, Tim R., Marie, Suely Kazue Nagahashi, Lindahl, Erik, Gahman, Timothy C., Shiau, Andrew K., Zhou, Huilin, DeGroot, John, Sulman, Erik P., Cavenee, Webster K., Kolodner, Richard D., Chen, Clark C., Furnari, Frank B.
Veröffentlicht in Cancer Cell (2019)

Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair

von Ma, Jianhui, Benitez, Jorge A., Li, Jie, Miki, Shunichiro, Ponte de Albuquerque, Claudio, Galatro, Thais, Orellana, Laura, Zanca, Ciro, Reed, Rachel, Boyer, Antonia, Koga, Tomoyuki, Varki, Nissi M., Fenton, Tim R., Nagahashi Marie, Suely Kazue, Lindahl, Erik, Gahman, Timothy C., Shiau, Andrew K., Zhou, Huilin, DeGroot, John, Sulman, Erik P., Cavenee, Webster K., Kolodner, Richard D., Chen, Clark C., Furnari, Frank B.
Veröffentlicht in Cancer Cell (2019)

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

von Villa, Genaro R., Hulce, Jonathan J., Zanca, Ciro, Bi, Junfeng, Ikegami, Shiro, Cahill, Gabrielle L., Gu, Yuchao, Lum, Kenneth M., Masui, Kenta, Yang, Huijun, Rong, Xin, Hong, Cynthia, Turner, Kristen M., Liu, Feng, Hon, Gary C., Jenkins, David, Martini, Michael, Armando, Aaron M., Quehenberger, Oswald, Cloughesy, Timothy F., Furnari, Frank B., Cavenee, Webster K., Tontonoz, Peter, Gahman, Timothy C., Shiau, Andrew K., Cravatt, Benjamin F., Mischel, Paul S.
Veröffentlicht in Cancer Cell (2016)

Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity

von Zanca, Ciro, Villa, Genaro R., Benitez, Jorge A., Thorne, Amy Haseley, Koga, Tomoyuki, D'Antonio, Matteo, Ikegami, Shiro, Ma, Jianhui, Boyer, Antonia D., Banisadr, Afsheen, Jameson, Nathan M., Parisian, Alison D., Eliseeva, Olesja V., Barnabe, Gabriela F., Liu, Feng, Wu, Sihan, Yang, Huijun, Wykosky, Jill, Frazer, Kelly A., Verkhusha, Vladislav V., Isaguliants, Maria G., Weiss, William A., Gahman, Timothy C., Shiau, Andrew K., Chen, Clark C., Mischel, Paul S., Cavenee, Webster K., Furnari, Frank B.
Veröffentlicht in Genes Dev (2017)