Analysis of Sequence Conservation at Nucleotide Resolution

Por Asthana, Saurabh, Roytberg, Mikhail, Stamatoyannopoulos, John, Sunyaev, Shamil
Publicado em 2007

Predicting Protein Complex Membership Using Probabilistic Network Reliability

Por Asthana, Saurabh, King, Oliver D., Gibbons, Francis D., Roth, Frederick P.
Publicado em 2004

Whole Exome Sequencing of Growing and Non-Growing Cutaneous Neurofibromas from a Single Patient with Neurofibromatosis Type 1

Por Faden, Daniel L., Asthana, Saurabh, Tihan, Tarik, DeRisi, Joseph, Kliot, Michel
Publicado no PLoS One (2017)

Correction: Whole Exome Sequencing of Growing and Non-Growing Cutaneous Neurofibromas from a Single Patient with Neurofibromatosis Type 1

Por Faden, Daniel L., Asthana, Saurabh, Tihan, Tarik, DeRisi, Joseph, Kliot, Michel
Publicado no PLoS One (2017)

Widely distributed noncoding purifying selection in the human genome

Por Asthana, Saurabh, Noble, William S., Kryukov, Gregory, Grant, Charles E., Sunyaev, Shamil, Stamatoyannopoulos, John A.
Publicado em 2007

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

Por Chang, Matthew T., Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H., Chapman, Jocelyn S., Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D., Solit, David B., Olshen, Adam B., Schultz, Nikolaus, Taylor, Barry S.
Publicado no Nat Biotechnol (2015)

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

Por Jonsson, Vanessa D., Blakely, Collin M., Lin, Luping, Asthana, Saurabh, Matni, Nikolai, Olivas, Victor, Pazarentzos, Evangelos, Gubens, Matthew A., Bastian, Boris C., Taylor, Barry S., Doyle, John C., Bivona, Trever G.
Publicado no Sci Rep (2017)

Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer

Por Lin, Luping, Asthana, Saurabh, Chan, Elton, Bandyopadhyay, Sourav, Martins, Maria M., Olivas, Victor, Yan, Jenny Jiacheng, Pham, Luu, Wang, Mingxue Michelle, Bollag, Gideon, Solit, David B., Collisson, Eric A., Rudin, Charles M., Taylor, Barry S., Bivona, Trever G.
Publicado em 2014

Combined chemical–genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma

Por Sabnis, Amit J., Guerriero, Christopher J., Olivas, Victor, Sayana, Anin, Shue, Jonathan, Flanagan, Jennifer, Asthana, Saurabh, Paton, Adrienne W., Paton, James C., Gestwicki, Jason E., Walter, Peter, Weissman, Jonathan S., Wipf, Peter, Brodsky, Jeffrey L., Bivona, Trever G.
Publicado no Proc Natl Acad Sci U S A (2016)

GE-15 CLONAL EVOLUTION AND INTRATUMORAL HETEROGENEITY OF LOW-GRADE GLIOMA GENOMES

Por Johnson, Brett, Mazor, Tali, Hong, Chibo, Barnes, Michael, Yamamoto, Shogo, Ueda, Hiroki, Tatsuno, Kenji, Aihara, Koki, Asthana, Saurabh, Dayal, Manisha, Nelson, Sarah, Phillips, Joanna, Bollen, Andrew, Mukasa, Akitake, Saito, Nobuhito, Aburatani, Hiroyuki, Berger, Mitchel, Chang, Susan, Taylor, Barry, Costello, Joseph
Publicado em 2014

Inactivation of Capicua drives cancer metastasis

Por Okimoto, Ross A., Breitenbuecher, Frank, Olivas, Victor R., Wu, Wei, Gini, Beatrice, Hofree, Matan, Asthana, Saurabh, Hrustanovic, Gorjan, Flanagan, Jennifer, Tulpule, Asmin, Blakely, Collin M., Haringsma, Henry J., Simmons, Andrew D., Gowen, Kyle, Suh, James, Miller, Vincent A., Ali, Siraj, Schuler, Martin, Bivona, Trever G.
Publicado no Nat Genet (2016)

NF-κB activating complex engaged in response to EGFR oncogene inhibition drives tumor cell survival and residual disease in lung cancer

Por Blakely, Collin M., Pazarentzos, Evangelos, Olivas, Victor, Asthana, Saurabh, Yan, Jenny Jiacheng, Tan, Irena, Hrustanovic, Gorjan, Chan, Elton, Lin, Luping, Neel, Dana S., Newton, William, Bobb, Kathryn, Fouts, Timothy, Meshulam, Jeffrey, Gubens, Matthew A., Jablons, David M., Johnson, Jeffrey R., Bandyopadhyay, Sourav, Krogan, Nevan J., Bivona, Trever G.
Publicado no Cell Rep (2015)

Synthetic lethality in ATM-deficient RAD50-mutant tumors underlie outlier response to cancer therapy

Por Al-Ahmadie, Hikmat, Iyer, Gopa, Hohl, Marcel, Asthana, Saurabh, Inagaki, Akiko, Schultz, Nikolaus, Hanrahan, Aphrothiti J., Scott, Sasinya N., Brannon, A. Rose, McDermott, Gregory C., Pirun, Mono, Ostrovnaya, Irina, Kim, Philip, Socci, Nicholas D., Viale, Agnes, Schwartz, Gary K., Reuter, Victor, Bochner, Bernard H., Rosenberg, Jonathan E., Bajorin, Dean F., Berger, Michael F., Petrini, John H.J., Solit, David B., Taylor, Barry S.
Publicado em 2014

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer

Por Hrustanovic, Gorjan, Olivas, Victor, Pazarentzos, Evangelos, Tulpule, Asmin, Asthana, Saurabh, Blakely, Collin M, Okimoto, Ross A, Lin, Luping, Neel, Dana S, Sabnis, Amit, Flanagan, Jennifer, Chan, Elton, Varella-Garcia, Marileila, Aisner, Dara L, Vaishnavi, Aria, Ou, Sai-Hong I, Collisson, Eric A, Ichihara, Eiki, Mack, Philip C, Lovly, Christine M, Karachaliou, Niki, Rosell, Rafael, Riess, Jonathan W, Doebele, Robert C, Bivona, Trever G
Publicado no Nat Med (2015)

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

Por Lin, Luping, Sabnis, Amit J, Chan, Elton, Olivas, Victor, Cade, Lindsay, Pazarentzos, Evangelos, Asthana, Saurabh, Neel, Dana, Yan, Jenny Jiacheng, Lu, Xinyuan, Pham, Luu, Wang, Mingxue M, Karachaliou, Niki, Cao, Maria Gonzalez, Manzano, Jose Luis, Ramirez, Jose Luis, Torres, Jose Miguel Sanchez, Buttitta, Fiamma, Rudin, Charles M, Collisson, Eric A, Algazi, Alain, Robinson, Eric, Osman, Iman, Muñoz-Couselo, Eva, Cortes, Javier, Frederick, Dennie T, Cooper, Zachary A, McMahon, Martin, Marchetti, Antonio, Rosell, Rafael, Flaherty, Keith T, Wargo, Jennifer A, Bivona, Trever G
Publicado no Nat Genet (2015)

Mutational Analysis Reveals the Origin and Therapy-driven Evolution of Recurrent Glioma

Por Johnson, Brett E., Mazor, Tali, Hong, Chibo, Barnes, Michael, Aihara, Koki, McLean, Cory Y., Fouse, Shaun D., Yamamoto, Shogo, Ueda, Hiroki, Tatsuno, Kenji, Asthana, Saurabh, Jalbert, Llewellyn E., Nelson, Sarah J., Bollen, Andrew W., Gustafson, W. Clay, Charron, Elise, Weiss, William A., Smirnov, Ivan V., Song, Jun S., Olshen, Adam B., Cha, Soonmee, Zhao, Yongjun, Moore, Richard A., Mungall, Andrew J., Jones, Steven J.M., Hirst, Martin, Marra, Marco A., Saito, Nobuhito, Aburatani, Hiroyuki, Mukasa, Akitake, Berger, Mitchel S., Chang, Susan M., Taylor, Barry S., Costello, Joseph F.
Publicado em 2013