Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

The success of targeted cancer therapy is limited by drug resistance that can result from tumor genetic heterogeneity. The current approach to address resistance typically involves initiating a new treatment after clinical/radiographic disease progression, ultimately resulting in futility in most pa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Jonsson, Vanessa D., Blakely, Collin M., Lin, Luping, Asthana, Saurabh, Matni, Nikolai, Olivas, Victor, Pazarentzos, Evangelos, Gubens, Matthew A., Bastian, Boris C., Taylor, Barry S., Doyle, John C., Bivona, Trever G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347024/
https://ncbi.nlm.nih.gov/pubmed/28287179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44206
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi