Inhibitors of Protein-Protein Interactions (PPIs): An Analysis of Scaffold Choices and Buried Surface Area

by Ran, Xu, Gestwicki, Jason E.
Published in Curr Opin Chem Biol (2018)

Inhibitors and chemical probes for molecular chaperone networks

by Gestwicki, Jason E., Shao, Hao
Published in J Biol Chem (2019)

Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98

by Shao, Hao, Gestwicki, Jason E.
Published in Bioorg Med Chem Lett (2020)

Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines

by Evans, Christopher G., Gestwicki, Jason E.
Published 2009

Insight into Amyloid Structure Using Chemical Probes

by Reinke, Ashley A., Gestwicki, Jason E.
Published 2011

Expanding the Number of “Druggable” Targets: Non-Enzymes and Protein-Protein Interactions

by Makley, Leah N., Gestwicki, Jason E.
Published 2013

Features of Protein-Protein Interactions that Translate into Potent Inhibitors: Topology, Surface Area and Affinity

by Smith, Matthew C., Gestwicki, Jason E.
Published 2012

Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro

by Rauch, Jennifer N., Gestwicki, Jason E.
Published 2014

Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds: Miniperspective

by Dunyak, Bryan M., Gestwicki, Jason E.
Published in J Med Chem (2016)

Retraction of “Enantioselective Organocatalytic Hantzsch Synthesis of Polyhydroquinolines”

by Evans, Christopher G., Gestwicki, Jason E.
Published in Org Lett (2021)

Pharmacological Targeting of the Hsp70 Chaperone

by Patury, Srikanth, Miyata, Yoshinari, Gestwicki, Jason E.
Published 2009

Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones

by Gillies, Anne, Taylor, Rebecca, Gestwicki, Jason E.
Published 2012

Backbone and methyl resonance assignments of the 42 kDa human Hsc70 nucleotide binding domain in the ADP state

by Zuiderweg, Erik R. P., Gestwicki, Jason E.
Published in Biomol NMR Assign (2016)

Aim for the Core: Suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

by Opoku-Nsiah, Kwadwo A., Gestwicki, Jason E.
Published in Transl Res (2018)

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

by Evans, Christopher G., Chang, Lyra, Gestwicki, Jason E.
Published 2010

Therapeutic Strategies for Restoring Tau Homeostasis

by Young, Zapporah T., Mok, Sue Ann, Gestwicki, Jason E.
Published in Cold Spring Harb Perspect Med (2018)

From Fuzzy to Function: The New Frontier of Protein–Protein Interactions

by Pricer, Rachel, Gestwicki, Jason E, Mapp, Anna K
Published in Acc Chem Res (2017)

Luminescence Complementation Assay for Measurement of Binding to Protein C-Termini in Live Cells

by Nadel, Cory M., Ran, Xu, Gestwicki, Jason E.
Published in Anal Biochem (2020)

A Chemical Screening Approach Reveals that Indole Flourescence is Quenched by Pre-Fibrillar But Not Fibrillar Amyloid-β

by Reinke, Ashley A., Seh, Han Yiau, Gestwicki, Jason E.
Published 2009

Synthetic Multivalent Ligands as Probes of Signal Transduction

by Kiessling, Laura L., Gestwicki, Jason E., Strong, Laura E.
Published 2006