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Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity
Mutational hotspots indicate selective pressure across a population of tumor samples, but their prevalence within and across cancer types is incompletely characterized. An approach to detect significantly mutated residues, rather than methods that identify recurrently mutated genes, may uncover new...
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| I publikationen: | Nat Biotechnol |
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| Huvudupphovsmän: | , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744099/ https://ncbi.nlm.nih.gov/pubmed/26619011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3391 |
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