GE-15 CLONAL EVOLUTION AND INTRATUMORAL HETEROGENEITY OF LOW-GRADE GLIOMA GENOMES

Low-grade gliomas frequently recur after surgical resection and may undergo malignant progression to a higher grade with a significantly worse prognosis. Understanding the origin and evolution of recurrences is critical for effectively treating residual disease to delay or prevent recurrence. Here,...

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Main Authors: Johnson, Brett, Mazor, Tali, Hong, Chibo, Barnes, Michael, Yamamoto, Shogo, Ueda, Hiroki, Tatsuno, Kenji, Aihara, Koki, Asthana, Saurabh, Dayal, Manisha, Nelson, Sarah, Phillips, Joanna, Bollen, Andrew, Mukasa, Akitake, Saito, Nobuhito, Aburatani, Hiroyuki, Berger, Mitchel, Chang, Susan, Taylor, Barry, Costello, Joseph
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218179/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.15
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