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MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation

MicroRNAs (miRNAs) have an important role in the development of chemosensitivity or chemoresistance in different types of cancer. Activation of the ERK1/2 pathway is a major determinant of diverse cellular processes and cancer development and is responsible for the transcription of several important...

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Autors principals: Romano, Giulia, Acunzo, Mario, Garofalo, Michela, Di Leva, Gianpiero, Cascione, Luciano, Zanca, Ciro, Bolon, Brad, Condorelli, Gerolama, Croce, Carlo M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478630/
https://ncbi.nlm.nih.gov/pubmed/23012423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207917109
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