MiR-221&222 regulate TRAIL-resistance and enhance tumorigenicity through PTEN and TIMP3 down-regulation

Lung and liver cancers are among the most deadly types of cancer. Despite improvements in treatment over the past few decades, patient survival remains poor, underlining the need for development of targeted therapies. MicroRNAs represent a class of small RNAs, frequently deregulated in human maligna...

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Main Authors: Garofalo, Michela, Leva, Gianpiero Di, Romano, Giulia, Nuovo, Gerard, Suh, Sung-Suk, Ngankeu, Apollinaire, Taccioli, Cristian, Pichiorri, Flavia, Alder, Hansjuerg, Secchiero, Paola, Gasparini, Pierluigi, Gonelli, Arianna, Costinean, Stefan, Acunzo, Mario, Condorelli, Gerolama, Croce, Carlo Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796583/
https://ncbi.nlm.nih.gov/pubmed/19962668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.10.014
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