MiR-221&222 regulate TRAIL-resistance and enhance tumorigenicity through PTEN and TIMP3 down-regulation

Lung and liver cancers are among the most deadly types of cancer. Despite improvements in treatment over the past few decades, patient survival remains poor, underlining the need for development of targeted therapies. MicroRNAs represent a class of small RNAs, frequently deregulated in human maligna...

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Bibliografische gegevens
Hoofdauteurs: Garofalo, Michela, Leva, Gianpiero Di, Romano, Giulia, Nuovo, Gerard, Suh, Sung-Suk, Ngankeu, Apollinaire, Taccioli, Cristian, Pichiorri, Flavia, Alder, Hansjuerg, Secchiero, Paola, Gasparini, Pierluigi, Gonelli, Arianna, Costinean, Stefan, Acunzo, Mario, Condorelli, Gerolama, Croce, Carlo Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796583/
https://ncbi.nlm.nih.gov/pubmed/19962668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.10.014
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