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MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer

BACKGROUND: Several lines of evidence have suggested that estrogen receptor α (ERα)–negative breast tumors, which are highly aggressive and nonresponsive to hormonal therapy, arise from ERα-positive precursors through different molecular pathways. Because microRNAs (miRNAs) modulate gene expression,...

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Detalhes bibliográficos
Main Authors: Di Leva, Gianpiero, Gasparini, Pierluigi, Piovan, Claudia, Ngankeu, Apollinaire, Garofalo, Michela, Taccioli, Cristian, Iorio, Marilena V., Li, Meng, Volinia, Stefano, Alder, Hansjuerg, Nakamura, Tatsuya, Nuovo, Gerard, Liu, Yunlong, Nephew, Kenneth P., Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873185/
https://ncbi.nlm.nih.gov/pubmed/20388878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq102
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