MiR-221&222 regulate TRAIL-resistance and enhance tumorigenicity through PTEN and TIMP3 down-regulation

Lung and liver cancers are among the most deadly types of cancer. Despite improvements in treatment over the past few decades, patient survival remains poor, underlining the need for development of targeted therapies. MicroRNAs represent a class of small RNAs, frequently deregulated in human maligna...

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Hlavní autoři: Garofalo, Michela, Leva, Gianpiero Di, Romano, Giulia, Nuovo, Gerard, Suh, Sung-Suk, Ngankeu, Apollinaire, Taccioli, Cristian, Pichiorri, Flavia, Alder, Hansjuerg, Secchiero, Paola, Gasparini, Pierluigi, Gonelli, Arianna, Costinean, Stefan, Acunzo, Mario, Condorelli, Gerolama, Croce, Carlo Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796583/
https://ncbi.nlm.nih.gov/pubmed/19962668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.10.014
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