AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

Fatty acid esters of hydroxy fatty acids (FAHFAs) are a newly discovered class of signaling lipids with anti-inflammatory and anti-diabetic properties. However, the endogenous regulation of FAHFAs remains a pressing but unanswered question. Here, using MS-based FAHFA hydrolysis assays, LC-MS–based l...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Erikci Ertunc, Meric, Kok, Bernard P., Parsons, William H., Wang, Justin G., Tan, Dan, Donaldson, Cynthia J., Pinto, Antonio F. M., Vaughan, Joan M., Ngo, Nhi, Lum, Kenneth M., Henry, Cassandra L., Coppola, Aundrea R., Niphakis, Micah J., Cravatt, Benjamin F., Saez, Enrique, Saghatelian, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196635/
https://ncbi.nlm.nih.gov/pubmed/32152231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012145
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