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AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

Fatty acid esters of hydroxy fatty acids (FAHFAs) are a newly discovered class of signaling lipids with anti-inflammatory and anti-diabetic properties. However, the endogenous regulation of FAHFAs remains a pressing but unanswered question. Here, using MS-based FAHFA hydrolysis assays, LC-MS–based l...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Erikci Ertunc, Meric, Kok, Bernard P., Parsons, William H., Wang, Justin G., Tan, Dan, Donaldson, Cynthia J., Pinto, Antonio F. M., Vaughan, Joan M., Ngo, Nhi, Lum, Kenneth M., Henry, Cassandra L., Coppola, Aundrea R., Niphakis, Micah J., Cravatt, Benjamin F., Saez, Enrique, Saghatelian, Alan
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196635/
https://ncbi.nlm.nih.gov/pubmed/32152231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012145
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