Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses

We recently discovered a structurally novel class of endogenous lipids, branched palmitic acid esters of hydroxy stearic acids (PAHSAs), with beneficial metabolic and anti-inflammatory effects. We tested whether PAHSAs protect against colitis, which is a chronic inflammatory disease driven predomina...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Lee, Jennifer, Moraes-Vieira, Pedro M., Castoldi, Angela, Aryal, Pratik, Yee, Eric U., Vickers, Christopher, Parnas, Oren, Donaldson, Cynthia J., Saghatelian, Alan, Kahn, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064000/
https://ncbi.nlm.nih.gov/pubmed/27573241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703835
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