Branched Fatty Acid Esters of Hydroxy Fatty Acids are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase

A recently discovered class of endogenous mammalian lipids, branched fatty acid esters of hydroxy fatty acids (FAHFAs), possess anti-diabetic and anti-inflammatory activities. Here, we identified and validated carboxyl ester lipase (CEL), a pancreatic enzyme hydrolyzing cholesteryl esters and other...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Kolar, Matthew J, Kamat, Siddhesh S, Parsons, William H, Homan, Edwin A., Maher, Tim, Peroni, Odile D., Syed, Ismail, Fjeld, Karianne, Molven, Anders, Kahn, Barbara B., Cravatt, Benjamin F., Saghatelian, Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056623/
https://ncbi.nlm.nih.gov/pubmed/27509211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00565
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