AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

Fatty acid esters of hydroxy fatty acids (FAHFAs) are a newly discovered class of signaling lipids with anti-inflammatory and anti-diabetic properties. However, the endogenous regulation of FAHFAs remains a pressing but unanswered question. Here, using MS-based FAHFA hydrolysis assays, LC-MS–based l...

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Vydáno v:J Biol Chem
Hlavní autoři: Erikci Ertunc, Meric, Kok, Bernard P., Parsons, William H., Wang, Justin G., Tan, Dan, Donaldson, Cynthia J., Pinto, Antonio F. M., Vaughan, Joan M., Ngo, Nhi, Lum, Kenneth M., Henry, Cassandra L., Coppola, Aundrea R., Niphakis, Micah J., Cravatt, Benjamin F., Saez, Enrique, Saghatelian, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Lipids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196635/
https://ncbi.nlm.nih.gov/pubmed/32152231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012145
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