A global map of lipid-binding proteins and their ligandability in cells

Lipids play central roles in physiology and disease, where their structural, metabolic, and signaling functions often arise from interactions with proteins. Here, we describe a set of lipid-based chemical proteomic probes and their global interaction map in mammalian cells. These interactions involv...

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Publicat a:Cell
Autors principals: Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Correia, Bruno E., Ichu, Taka-Aki, Olucha, Jose, Brown, Steven J., Kundu, Soumajit, Piscitelli, Fabiana, Rosen, Hugh, Cravatt, Benjamin F.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615699/
https://ncbi.nlm.nih.gov/pubmed/26091042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.045
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