A global map of lipid-binding proteins and their ligandability in cells

Lipids play central roles in physiology and disease, where their structural, metabolic, and signaling functions often arise from interactions with proteins. Here, we describe a set of lipid-based chemical proteomic probes and their global interaction map in mammalian cells. These interactions involv...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Correia, Bruno E., Ichu, Taka-Aki, Olucha, Jose, Brown, Steven J., Kundu, Soumajit, Piscitelli, Fabiana, Rosen, Hugh, Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615699/
https://ncbi.nlm.nih.gov/pubmed/26091042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.045
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