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Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone
[Image: see text] Flavaglines are a class of natural products with potent insecticidal and anticancer activities. β-Lactones are a privileged structural motif found in both therapeutic agents and chemical probes. Herein, we report the synthesis, unexpected light-driven di-epimerization, and activity...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2014
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978386/ https://ncbi.nlm.nih.gov/pubmed/24447064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412431g |
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