ロード中...
Combining cross-metathesis and activity-based protein profiling: New β-lactone motifs for targeting serine hydrolases
β-Lactones are a privileged structural motif as enzyme inhibitors and chemical probes, particularly for the inhibition of enzymes from the serine hydrolase class. Herein, we demonstrate that cross-metathesis (CM) of α-methylene-β-lactones offers rapid access to structurally diverse, previously unexp...
保存先:
| 出版年: | Bioorg Med Chem Lett |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4279111/ https://ncbi.nlm.nih.gov/pubmed/25541002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.038 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|