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The Pharmacological Landscape and Therapeutic Potential of Serine Hydrolases

Serine hydrolases play critical roles in many biological processes, and several are targets of approved drugs for indications such as type 2 diabetes, Alzheimer’s disease, and infectious disease. Despite this, most of the 200+ human serine hydrolases remain poorly characterized with respect to their...

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Detalhes bibliográficos
Main Authors: Bachovchin, Daniel A., Cravatt, Benjamin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665514/
https://ncbi.nlm.nih.gov/pubmed/22212679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3620
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