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Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders
BACKGROUND: Fatty acid amide hydrolase (FAAH) is an integral membrane enzyme that hydrolyzes the endocannabinoid anandamide and related amidated signaling lipids. Genetic or pharmacological inactivation of FAAH produces analgesic, anti-inflammatory, anxiolytic, and antidepressant phenotypes without...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882713/ https://ncbi.nlm.nih.gov/pubmed/20544003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460440903018857 |
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