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Targeting Fatty Acid Amide Hydrolase (FAAH) to Treat Pain and Inflammation

The endogenous cannabinoid N-arachidonoyl ethanolamine (anandamide; AEA) produces most of its pharmacological effects by binding and activating CB(1) and CB(2) cannabinoid receptors within the CNS and periphery. However, the actions of AEA are short lived because of its rapid catabolism by fatty aci...

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Hlavní autoři: Schlosburg, Joel E., Kinsey, Steven G., Lichtman, Aron H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664876/
https://ncbi.nlm.nih.gov/pubmed/19184452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9075-y
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