Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders

Por Ahn, Kay, Johnson, Douglas S., Cravatt, Benjamin F.
Publicado em 2009

Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System

Por Ahn, Kay, McKinney, Michele K., Cravatt, Benjamin F.
Publicado em 2008

Structure-guided inhibitor design for human FAAH by interspecies active site conversion

Por Mileni, Mauro, Johnson, Douglas S., Wang, Zhigang, Everdeen, Daniel S., Liimatta, Marya, Pabst, Brandon, Bhattacharya, Keshab, Nugent, Richard A., Kamtekar, Satwik, Cravatt, Benjamin F., Ahn, Kay, Stevens, Raymond C.
Publicado em 2008

Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

Por Hall, Angela M., Kou, Kou, Chen, Zhouji, Pietka, Terri A., Kumar, Mrudula, Korenblat, Kevin M., Lee, Kyuha, Ahn, Kay, Fabbrini, Elisa, Klein, Samuel, Goodwin, Bryan, Finck, Brian N.
Publicado em 2012

Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)

Por Johnson, Douglas S., Ahn, Kay, Kesten, Suzanne, Lazerwith, Scott E., Song, Yuntao, Morris, Mark, Fay, Lorraine, Gregory, Tracy, Stiff, Cory, Dunbar, James B., Liimatta, Marya, Beidler, David, Smith, Sarah, Nomanbhoy, Tyzoon K., Cravatt, Benjamin F.
Publicado em 2009

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

Por Pacholec, Michelle, Bleasdale, John E., Chrunyk, Boris, Cunningham, David, Flynn, Declan, Garofalo, Robert S., Griffith, David, Griffor, Matt, Loulakis, Pat, Pabst, Brandon, Qiu, Xiayang, Stockman, Brian, Thanabal, Venkataraman, Varghese, Alison, Ward, Jessica, Withka, Jane, Ahn, Kay
Publicado em 2010

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor

Por Johnson, Douglas S., Stiff, Cory, Lazerwith, Scott E., Kesten, Suzanne R., Fay, Lorraine K., Morris, Mark, Beidler, David, Liimatta, Marya B., Smith, Sarah E., Dudley, David T., Sadagopan, Nalini, Bhattachar, Shobha N., Kesten, Stephen J., Nomanbhoy, Tyzoon K., Cravatt, Benjamin F., Ahn, Kay
Publicado em 2010

The synthesis and in vivo evaluation of [(18)F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)

Por Skaddan, Marc B., Zhang, Lei, Johnson, Douglas S., Zhu, Aijun, Zasadny, Kenneth R., Coelho, Richard V., Kuszpit, Kyle, Currier, Gwen, Fan, Kuo-Hsien, Beck, Elizabeth M., Chen, Laigao, Drozda, Susan E., Balan, Gayatri, Niphakis, Micah, Cravatt, Benjamin F., Ahn, Kay, Bocan, Thomas, Villalobos, Anabella
Publicado em 2012

Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain

Por Ahn, Kay, Johnson, Douglas S., Mileni, Mauro, Beidler, David, Long, Jonathan Z., McKinney, Michele K., Weerapana, Eranthie, Sadagopan, Nalini, Liimatta, Marya, Smith, Sarah E., Lazerwith, Scott, Stiff, Cory, Kamtekar, Satwik, Bhattacharya, Keshab, Zhang, Yanhua, Swaney, Stephen, Van Becelaere, Keri, Stevens, Raymond C., Cravatt, Benjamin F.
Publicado em 2009

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pa...

Por Ahn, Kay, Smith, Sarah E., Liimatta, Marya B., Beidler, David, Sadagopan, Nalini, Dudley, David T., Young, Tim, Wren, Paul, Zhang, Yanhua, Swaney, Steven, Van Becelaere, Keri, Blankman, Jacqueline L., Nomura, Daniel K., Bhattachar, Shobha N., Stiff, Cory, Nomanbhoy, Tyzoon K., Weerapana, Eranthie, Johnson, Douglas S., Cravatt, Benjamin F.
Publicado em 2011