Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain

Lignende værker

• Structure-guided inhibitor design for human FAAH by interspecies active site conversion
  af: Mileni, Mauro, et al.
  Udgivet: (2008)
• Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor
  af: Johnson, Douglas S., et al.
  Udgivet: (2010)
• Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain
  af: Ahn, Kay, et al.
  Udgivet: (2011)
• Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)
  af: Johnson, Douglas S., et al.
  Udgivet: (2009)
• Crystal Structures of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation
  af: Mileni, Mauro, et al.
  Udgivet: (2010)