Structure-guided inhibitor design for human FAAH by interspecies active site conversion

Samankaltaisia teoksia

• Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain
  Tekijä: Ahn, Kay, et al.
  Julkaistu: (2009)
• Crystal Structures of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of a Deacylating Water Molecule and Insight into Enzyme Inactivation
  Tekijä: Mileni, Mauro, et al.
  Julkaistu: (2010)
• Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)
  Tekijä: Johnson, Douglas S., et al.
  Julkaistu: (2009)
• Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor
  Tekijä: Johnson, Douglas S., et al.
  Julkaistu: (2010)
• Just Add Water: Cannabinoid Discrimination in a Water T-Maze with FAAH((−/−)) and FAAH((+/+)) Mice
  Tekijä: Wiley, Jenny L., et al.
  Julkaistu: (2016)