SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

Sirtuins catalyze NAD(+)-dependent protein deacetylation and are critical regulators of transcription, apoptosis, metabolism, and aging. There are seven human sirtuins (SIRT1–7), and SIRT1 has been implicated as a key mediator of the pathways downstream of calorie restriction that have been shown to...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Pacholec, Michelle, Bleasdale, John E., Chrunyk, Boris, Cunningham, David, Flynn, Declan, Garofalo, Robert S., Griffith, David, Griffor, Matt, Loulakis, Pat, Pabst, Brandon, Qiu, Xiayang, Stockman, Brian, Thanabal, Venkataraman, Varghese, Alison, Ward, Jessica, Withka, Jane, Ahn, Kay
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2010
الموضوعات:
Enzymology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832984/
https://ncbi.nlm.nih.gov/pubmed/20061378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.088682
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