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SRT2183 impairs ovarian cancer by facilitating autophagy

The 5-year survival rate of ovarian cancer patients is only 47%, and developing novel drugs for ovarian cancer is needed. Herein, we evaluated if and how SRT2183, a sirtuin-1 activator, impairs the ovarian cancer cells. OVCAR-3 and A2780 cells were treated with SRT2183. Cell viability was measured b...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Sun, Tingting, Hu, Yanfen, He, Weipeng, Shang, Yuru, Yang, Xiaohong, Gong, Liyun, Zhang, Xianbin, Gong, Peng, Yang, Guofen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762476/
https://ncbi.nlm.nih.gov/pubmed/33223507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104126
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