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Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway

BACKGROUND: Glioblastoma (GBM) is an extremely deadly form of brain cancer with limited treatment options and thus novel therapeutic modalities are necessary. Histone deacetylase inhibitors (HDACi) have demonstrated clinical and preclinical activities against GBM. (Silent mating type information reg...

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Vydáno v:BMC Cancer
Hlavní autoři: Ye, Tian, Wei, Liwen, Shi, Ji, Jiang, Ke, Xu, Huizhe, Hu, Lulu, Kong, Lingkai, Zhang, Ye, Meng, Songshu, Piao, Haozhe
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637499/
https://ncbi.nlm.nih.gov/pubmed/31319814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5852-5
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