Sirtuin 1 activator SRT2104 protects Huntington's disease mice

Sirtuin 1 is a nicotinamide adenine dinucleotide-dependent protein deacetylase which regulates longevity and improves metabolism. Activation of Sirtuin 1 confers beneficial effects in models of neurodegenerative diseases. We and others have provided convincing evidence that overexpression of Sirtuin...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Jiang, Mali, Zheng, Jennifer, Peng, Qi, Hou, Zhipeng, Zhang, Jiangyang, Mori, Susumu, Ellis, James L, Vlasuk, George P, Fries, Harvey, Suri, Vipin, Duan, Wenzhen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284130/
https://ncbi.nlm.nih.gov/pubmed/25574479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.135
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