Targeting Sirtuin-1 in Huntington’s disease: Rationale and Current Status

מאת Duan, Wenzhen
יצא לאור 2013

Sirtuins: from metabolic regulation to brain aging

מאת Duan, Wenzhen
יצא לאור 2013

Metabolism in HD - Still a relevant mechanism?

מאת Duan, Wenzhen, Jiang, Mali, Jin, Jing
יצא לאור 2014

Prophylactic Activation of Neuroprotective Stress Response Pathways by Dietary and Behavioral Manipulations

מאת Mattson, Mark P., Duan, Wenzhen, Wan, Ruqian, Guo, Zhihong
יצא לאור 2004

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

מאת Duan, Wenzhen, Guo, Zhihong, Jiang, Haiyang, Ware, Melvin, Li, Xiao-Jiang, Mattson, Mark P.
יצא לאור 2003

The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington’s disease mouse model

מאת Peng, Qi, Masuda, Naoki, Jiang, Mali, Li, Qing, Zhao, Ming, Ross, Christopher A., Duan, Wenzhen
יצא לאור 2007

Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington’s Disease

מאת Peng, Qi, Wu, Bin, Jiang, Mali, Jin, Jing, Hou, Zhipeng, Zheng, Jennifer, Zhang, Jiangyang, Duan, Wenzhen
הוצא לאור ב PLoS One (2016)

Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model

מאת Cheng, Yong, Peng, Qi, Hou, Zhipeng, Aggarwal, Manisha, Zhang, Jiangyang, Mori, Susumu, Ross, Christopher A., Duan, Wenzhen
יצא לאור 2011

Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington’s disease

מאת Jin, Jing, Albertz, Jennifer, Guo, Zhihong, Peng, Qi, Rudow, Gay, Troncoso, Juan C., Ross, Christopher A., Duan, Wenzhen
יצא לאור 2013

Resting-state functional MRI reveals altered brain connectivity and its correlation with motor dysfunction in a mouse model of Huntington’s disease

מאת Li, Qiang, Li, Gang, Wu, Dan, Lu, Hanbing, Hou, Zhipeng, Ross, Christopher A., Yang, Yihong, Zhang, Jiangyang, Duan, Wenzhen
הוצא לאור ב Sci Rep (2017)

Brain structure in juvenile-onset Huntington disease

מאת Tereshchenko, Alexander, Magnotta, Vincent, Epping, Eric, Mathews, Katherine, Espe-Pfeifer, Patricia, Martin, Erin, Dawson, Jeffrey, Duan, Wenzhen, Nopoulos, Peg
הוצא לאור ב Neurology (2019)

Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging

מאת Aggarwal, Manisha, Duan, Wenzhen, Hou, Zhipeng, Rakesh, Neal, Peng, Qi, Ross, Christopher A., Miller, Michael I., Mori, Susumu, Zhang, Jiangyang
יצא לאור 2012

Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin

מאת Jin, Jing, Cheng, Yong, Zhang, Yongqing, Wood, William, Peng, Qi, Hutchison, Emmette, Mattson, Mark P., Becker, Kevin G., Duan, Wenzhen
יצא לאור 2012

Metformin protects cells from mutant huntingtin toxicity through activation of AMPK and modulation of mitochondrial dynamics

מאת Jin, Jing, Gu, Hao, Anders, Nicole M., Ren, Tianhua, Jiang, Mali, Tao, Michael, Peng, Qi, Rudek, Michelle A., Duan, Wenzhen
הוצא לאור ב Neuromolecular Med (2016)

Early detection of Alzheimer’s disease using creatine chemical exchange saturation transfer magnetic resonance imaging

מאת Chen, Lin, van Zijl, Peter C.M., Wei, Zhiliang, Lu, Hanzhang, Duan, Wenzhen, Wong, Philip C., Li, Tong, Xu, Jiadi
הוצא לאור ב Neuroimage (2021)

Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease

מאת Masuda, Naoki, Peng, Qi, Li, Qing, Jiang, Mali, Liang, Yideng, Wang, Xiaofang, Zhao, Ming, Wang, Wenfei, Ross, Christopher A., Duan, Wenzhen
יצא לאור 2008

Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease

מאת Jiang, Mali, Peng, Qi, Liu, Xia, Jin, Jing, Hou, Zhipeng, Zhang, Jiangyang, Mori, Susumu, Ross, Christopher A., Ye, Keqiang, Duan, Wenzhen
יצא לאור 2013

Sertraline Slows Disease Progression and Increases Neurogenesis in N171-82Q mouse model of Huntington’s Disease

מאת Duan, Wenzhen, Peng, Qi, Masuda, Naoki, Ford, Eric, Tryggestad, Erik, Ladenheim, Bruce, Zhao, Ming, Cadet, Jean Lud, Wong, John, Ross, Christopher A.
יצא לאור 2008

Sirtuin 1 activator SRT2104 protects Huntington's disease mice

מאת Jiang, Mali, Zheng, Jennifer, Peng, Qi, Hou, Zhipeng, Zhang, Jiangyang, Mori, Susumu, Ellis, James L, Vlasuk, George P, Fries, Harvey, Suri, Vipin, Duan, Wenzhen
הוצא לאור ב Ann Clin Transl Neurol (2014)

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington’s disease

מאת Zhou, Xiao, Li, Gang, Kaplan, Anna, Gaschler, Michael M, Zhang, Xiaoyan, Hou, Zhipeng, Jiang, Mali, Zott, Roseann, Cremers, Serge, Stockwell, Brent R, Duan, Wenzhen
הוצא לאור ב Hum Mol Genet (2018)