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Metabolism in HD - Still a relevant mechanism?

The polyglutamine expansion within huntingtin is the causative factor in the pathogenesis of Huntington’s disease (HD). Although the underlying mechanisms by which mutant huntingtin causes neuronal dysfunction and degeneration have not been fully elucidated, the compelling evidence suggests that mit...

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Detalhes bibliográficos
Main Authors: Duan, Wenzhen, Jiang, Mali, Jin, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163071/
https://ncbi.nlm.nih.gov/pubmed/25124273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25992
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