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Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin

Emerging evidence indicates that microRNAs (miRNAs) may play an important role in the pathogenesis of Huntington’s disease (HD). To identify the individual miRNAs that are altered in HD and may therefore regulate a gene network underlying mutant huntingtin-induced neuronal dysfunction in HD, we perf...

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Detalhes bibliográficos
Main Authors: Jin, Jing, Cheng, Yong, Zhang, Yongqing, Wood, William, Peng, Qi, Hutchison, Emmette, Mattson, Mark P., Becker, Kevin G., Duan, Wenzhen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472040/
https://ncbi.nlm.nih.gov/pubmed/22906125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07925.x
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