Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3-phosphate. However, an alternative pathway for sy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hall, Angela M., Kou, Kou, Chen, Zhouji, Pietka, Terri A., Kumar, Mrudula, Korenblat, Kevin M., Lee, Kyuha, Ahn, Kay, Fabbrini, Elisa, Klein, Samuel, Goodwin, Bryan, Finck, Brian N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Patient-Oriented and Epidemiological Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329399/
https://ncbi.nlm.nih.gov/pubmed/22394502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P025536
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